Knowra Adverse drug reaction Adverse drug reaction An adverse drug reaction is an unintended harmful response to a medicine taken at a normal dose. It differs from harm caused by overdose, misuse, or medication error.
Type A and Type B adverse drug reactions : A classification separating predictable, dose-related drug reactions from less predictable reactions unrelated to ordinary pharmacological effects. This classification explains why some reactions follow dose while others arise unpredictably.
Pharmacovigilance : The detection, assessment, understanding, and prevention of harmful effects or other medicine-related problems. It gathers reports and evidence to identify risks that were missed before approval.
Medication adherence : The extent to which a person takes medicines as agreed with a healthcare professional. Fear or experience of harmful reactions can lead people to skip or stop treatment.
Side effect : A secondary effect of a medicine, which may be harmful, beneficial, or neither. The term is often used loosely, but an adverse reaction specifically denotes harm at normal use.
Underreporting of adverse drug reactions : The failure to report suspected harmful responses to medicines to surveillance systems or authorities. Missing reports obscure the frequency and patterns of reactions after medicines reach the public.
Drug allergy : An immune-mediated harmful response to a medicine or one of its components. Allergy is one specific mechanism behind adverse drug reactions, often involving immune recognition.
Adverse event : An unfavorable medical occurrence during treatment, whether or not the treatment caused it. Unlike an adverse drug reaction, an adverse event does not imply a causal link to the medicine.
Deprescribing : The planned reduction or stopping of medicines when their potential harms outweigh their benefits. A serious or persistent reaction may make supervised dose reduction or discontinuation appropriate.
Medication error : A preventable mistake in prescribing, dispensing, or administering a medicine. Errors can cause harm, but they are distinct from reactions occurring despite correct use.
Real-world evidence : Clinical evidence derived from routinely collected data about health and healthcare outside traditional trials. It can reveal reaction patterns across broader populations and longer periods than trials allow.
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