Knowra Alprazolam Alprazolam Alprazolam is a short-acting benzodiazepine medication prescribed for anxiety disorders and panic disorder. It enhances inhibitory signaling in the brain and can cause dependence.
GABA receptor : A family of receptors that respond to gamma-aminobutyric acid, the brain’s principal inhibitory neurotransmitter. Alprazolam strengthens inhibitory signaling through GABA-A receptors.
Generalized anxiety disorder : A disorder involving persistent, excessive worry across multiple areas of life. Alprazolam is prescribed for anxiety symptoms, though long-term management often favors other treatments.
Benzodiazepine dependence : A state of physical adaptation to benzodiazepines that can produce withdrawal symptoms when use is reduced or stopped. Regular alprazolam use can lead to physical dependence, even when taken as prescribed.
Diazepam : A long-acting benzodiazepine used for anxiety, muscle spasms, seizures, and alcohol withdrawal. Diazepam lasts longer and has active metabolites, unlike alprazolam’s shorter action.
GABA-A receptor positive allosteric modulator : A substance that increases GABA-A receptor responses without directly activating the receptor’s GABA-binding site. Alprazolam binds a separate site and amplifies GABA’s effect.
Panic disorder : A disorder marked by recurrent unexpected panic attacks and persistent concern about further attacks. Alprazolam is used to treat panic disorder and can reduce acute symptoms.
Benzodiazepine withdrawal syndrome : A cluster of symptoms following reduction or cessation of benzodiazepines after sustained use. Abruptly stopping alprazolam can cause severe withdrawal, including seizures.
Lorazepam : A benzodiazepine used for anxiety, seizures, and procedural sedation. Lorazepam is metabolized differently and is often chosen when liver metabolism is a concern.
Pharmacokinetics : The study of how a substance is absorbed, distributed, metabolized, and eliminated by the body. Absorption and clearance help explain alprazolam’s onset and duration.
Extended-release formulation : A dosage form designed to release a drug gradually over an extended period. Extended-release alprazolam is taken less frequently than immediate-release tablets.
Show all 22