Knowra Biologic therapy Biologic therapy Biologic therapy uses medicines made from living systems or engineered biological molecules to alter disease pathways, often by targeting specific molecules or cells.
Monoclonal antibody : A laboratory-produced antibody designed to bind a particular molecular target. Many biologic therapies use antibodies to bind disease-associated molecules or cells.
Tumor necrosis factor inhibitor : A medicine that blocks tumor necrosis factor, an inflammatory signaling protein. These biologics are widely used to suppress inflammation in autoimmune diseases.
Recombinant DNA : DNA assembled from sequences originating in different sources, often used to produce proteins in cells. Recombinant DNA methods enable cells to manufacture many therapeutic proteins.
Small-molecule drug : A medicine made of relatively small chemical compounds that can often enter cells and be taken orally. Small molecules commonly differ from biologics in size, production, route, and target access.
Antigen : A molecule or molecular structure that can be recognized by an antibody or immune receptor. Antibody biologics act by recognizing antigens on cells or in tissues.
Interleukin-6 inhibitor : A medicine that blocks interleukin-6 signaling, which contributes to inflammation and immune responses. Blocking this pathway treats several inflammatory conditions and can reduce severe immune activation.
Biopharmaceutical : A medicine produced using biological sources or processes, including proteins, cells, and nucleic acids. Biologic therapy uses biopharmaceuticals as its medicines.
Conventional synthetic disease-modifying antirheumatic drug : A chemically synthesized medicine that modifies disease activity, especially in inflammatory arthritis. These drugs offer an alternative to biologics for controlling autoimmune inflammation.
Receptor antagonist : A substance that binds a receptor and blocks or reduces its activation. Some biologics prevent disease signals by blocking receptors.
Checkpoint inhibitor : A cancer medicine that blocks inhibitory immune signals to strengthen antitumor T-cell activity. These biologics redirect immune activity against tumors rather than suppress it.
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