KnowraCytosineCytosineCytosine is a pyrimidine nucleobase found in DNA and RNA. It pairs with guanine through three hydrogen bonds.BriefConnectPyrimidine: A six-membered nitrogen-containing aromatic ring that forms the core of several biological molecules. Cytosine belongs to this ring-based chemical family.Guanine: A purine nucleobase that pairs with cytosine in DNA and RNA. Guanine forms cytosine’s standard complementary base pair.5-Methylcytosine: A methylated form of cytosine found in DNA and involved in epigenetic regulation. It is the principal modified cytosine measured in many DNA-methylation studies.Uracil: A pyrimidine nucleobase found in RNA that replaces thymine in standard RNA sequences. Uracil is cytosine’s deamination product and differs by lacking an amino group.Nucleobase: A nitrogen-containing molecule that forms part of the information-bearing components of nucleic acids. Cytosine is one of the bases used in DNA and RNA.Watson–Crick base pairing: The specific hydrogen-bonding patterns that pair complementary bases in nucleic acids. Its canonical pattern gives the cytosine–guanine pair three hydrogen bonds.Bisulfite sequencing: A DNA sequencing method that distinguishes methylated from unmethylated cytosines through bisulfite conversion. It maps cytosine methylation by converting most unmethylated cytosines to uracil.Thymine: A pyrimidine nucleobase used in DNA that pairs with adenine. Thymine is the other pyrimidine commonly found in DNA, but pairs with adenine.Nucleoside: A molecule consisting of a nucleobase joined to a sugar, without phosphate groups. Adding ribose or deoxyribose to cytosine produces a cytidine nucleoside.Cytosine tautomerism: The interconversion of cytosine between structural forms that differ in proton positions and double bonds. Rare cytosine tautomers can alter its hydrogen-bonding pattern.Show all 23Linked from 7 pagesPyrimidineBroader topic: Cytosine is one of the three canonical pyrimidine bases in nucleic acids.CytidineBroader topic: Cytosine alone lacks the ribose that makes the molecule a nucleoside.Albrecht KosselBroader topic: Kossel’s studies of nucleic-acid constituents contributed to its early chemical characterization.Show all 7