Knowra Eosinophilia Eosinophilia Eosinophilia is an elevated number of eosinophils in blood or tissue. It can arise from allergic disease, parasitic infection, medication reactions, and other conditions.
Eosinophil : A white blood cell involved in immune responses, especially against parasites and in allergic inflammation. Eosinophilia is defined by increased numbers of this cell type.
Absolute eosinophil count : The number of eosinophils per unit of blood, calculated from the total white blood cell count and eosinophil percentage. This measurement, rather than the percentage alone, defines blood eosinophilia.
Eosinopenia : A lower-than-normal number of eosinophils in blood. It is the opposite direction of the blood-count change.
Hypereosinophilic syndrome : A group of disorders involving sustained hypereosinophilia and eosinophil-related damage to one or more organs. It is considered when high eosinophil counts persist with attributable organ injury.
Interleukin 5 : A cytokine that promotes eosinophil development, survival, and activation. This signaling molecule can drive eosinophil production and accumulation.
Hypereosinophilia : A marked increase in blood eosinophils, commonly defined as an absolute count of at least 1,500 cells per microliter. Persistent high counts warrant evaluation for tissue damage and underlying disease.
Basophilia : An elevated number of basophils, another type of white blood cell, in blood. This names an increase in a different granulocyte, not eosinophils.
Clonal eosinophilia : Eosinophilia caused by an acquired genetic abnormality in blood-forming cells. Finding a clonal process changes classification and may identify targeted treatment.
Eosinophilopoiesis : The formation and maturation of eosinophils, primarily in bone marrow. Increased production is one route to an elevated eosinophil count.
Eosinophilic granulomatosis with polyangiitis : A rare vasculitis associated with asthma, eosinophilia, and inflammation of small- to medium-sized blood vessels. This systemic disease is a significant cause of eosinophilia with organ involvement.
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