KnowraHomozygousHomozygousHomozygous describes a genotype with two identical alleles at a particular locus, one inherited from each parent.BriefConnectAllele: One of two or more alternative forms of a DNA sequence at a particular genomic location. Homozygosity compares the alleles present at one locus.Heterozygous: Having two different alleles at a particular genetic locus. It is the direct alternative to having identical alleles at that locus.Mendelian inheritance: The transmission of alleles from parents to offspring according to patterns described by Gregor Mendel. Each parent contributes one allele to an offspring’s pair at many loci.Recessive allele: An allele whose associated phenotype is typically masked by a different allele in a heterozygote. A recessive allele often affects phenotype when present in a homozygous pair.Runs of homozygosity: Continuous genomic segments in which an individual carries identical alleles inherited from both parents. Long matching segments provide a measurable genomic form of homozygosity.Genotype: The genetic constitution of an organism, either across its genome or at specified loci. Homozygous names a particular relationship between alleles in a genotype.Hemizygous: Having only one copy of a gene or genomic region where two copies are usually present. A single allele copy cannot form a homozygous pair.Inbreeding: Reproduction between individuals that are more closely related than random members of a population. Related parents are more likely to carry the same ancestral allele.Autosomal recessive inheritance: A pattern in which a trait or disorder generally appears when both copies of an autosomal gene carry relevant variants. Homozygosity for a disease-associated variant can produce this inheritance pattern.Inbreeding depression: Reduced survival or reproduction associated with mating between related individuals or increased homozygosity. Greater homozygosity can expose deleterious recessive variants.Show all 25Linked from 1 pageManx catRelated: Embryos inheriting two copies of the Manx tail variant generally do not survive.