Hyperhidrosis

Hyperhidrosis is sweating excessive enough to exceed the body's needs for temperature regulation. It may be focal or generalized, and may occur without heat or exercise.

Eccrine sweat gland: A skin gland that releases watery sweat onto the surface, chiefly for cooling. Most primary hyperhidrosis involves overactivity of these glands.
Minor's starch–iodine test: A clinical test that maps sweating by turning iodine-treated skin dark where starch reacts with sweat. It can identify the precise area of excessive sweating before localized treatment.
Thermoregulation: The processes by which an organism maintains a suitable internal temperature. Hyperhidrosis is defined by sweating that exceeds what this cooling function requires.
Quality of life: A person's overall assessment of well-being across physical, psychological, and social life. Sweating that disrupts work, clothing, or relationships can substantially reduce it.
Sympathetic nervous system: A branch of the autonomic nervous system that regulates involuntary responses, including sweating. Sympathetic nerve signals stimulate sweat glands even when cooling is unnecessary.
Hyperhidrosis Disease Severity Scale: A four-point patient rating of how much sweating interferes with daily activities. It helps quantify symptom burden and track response to treatment.
Sweating: The release of fluid from skin glands, which can cool the body as it evaporates. Understanding normal sweating clarifies what makes the excessive form distinctive.
Social anxiety disorder: A mental health disorder involving persistent fear of scrutiny or negative judgment in social situations. Visible sweating may intensify social fears, though it does not itself establish this disorder.
Acetylcholine: A neurotransmitter that carries signals between nerve cells and activates several target tissues. It is the principal neurotransmitter driving eccrine sweat secretion.
Aluminum chloride: A topical antiperspirant ingredient that reduces sweat reaching the skin surface by obstructing sweat ducts. It is often used first for focal sweating, particularly in the underarms.

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