Hypericum perforatum

Hypericum perforatum, or common St John’s wort, is a flowering perennial plant native to Europe and parts of Asia. Its yellow flowers and leaves contain compounds used in herbal preparations.

Hypericaceae: Hypericaceae is a family of flowering plants that includes St John’s worts. This is the plant family that contains Hypericum perforatum.
Herbal medicine: Herbal medicine uses plants or plant extracts to prevent or treat health conditions. Traditional and modern preparations of this species are used as herbal remedies.
Hypericum perforatum morphology: Hypericum perforatum morphology is the species’ characteristic structure, including translucent leaf glands and yellow flowers. These traits help distinguish the plant from other yellow-flowered species.
Hypericum maculatum: Hypericum maculatum is a St John’s wort species with spotted leaves and stems, native to Europe and western Asia. It is a related species that can be confused with common St John’s wort.
Hypericum: Hypericum is a genus of flowering plants that includes St John’s worts. Hypericum perforatum is one species in this diverse genus.
Major depressive disorder: Major depressive disorder is a mental disorder characterized by persistent depressed mood or loss of interest and other symptoms. Some standardized St John’s wort extracts have been studied and used for mild to moderate depression.
Hypericum perforatum in North America: Hypericum perforatum in North America is an introduced plant that occurs in fields, roadsides, and other disturbed habitats. Its spread beyond its native range shows how the species can become a persistent weed.
Hypericum calycinum: Hypericum calycinum, or Aaron’s beard, is a low-growing St John’s wort commonly cultivated as ground cover. Its ornamental use contrasts with the medicinal focus often given to H. perforatum.
Hypericin: Hypericin is a red pigment and bioactive compound found in some Hypericum species. It contributes to the plant’s characteristic dark-red extracts and is studied for biological activity.
Drug interaction: A drug interaction occurs when one substance changes the effects or concentration of another. The plant can alter drug metabolism and reduce the effectiveness of several medicines.

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Herb–drug interactionBroader topic: It induces drug-metabolizing enzymes and transporters, reducing exposure to several medicines.