Knowra Kidney transplantation Kidney transplantation Kidney transplantation is surgery that places a donor kidney in a person with kidney failure. The transplanted kidney can take over much of the body's blood-filtering and fluid-regulating work.
Kidney transplant surgery : An operation that implants a donor kidney, usually in the lower abdomen, and connects its blood vessels and ureter. This procedure places the new kidney and connects it to circulation and urine drainage.
End-stage kidney disease : Advanced, irreversible loss of kidney function that generally requires dialysis or transplantation to sustain life. This is the condition for which kidney transplantation is a treatment option.
Kidney transplant survival : The probability that a transplanted kidney or its recipient remains alive over a specified period. Graft and patient survival measure different outcomes after transplantation.
Peritoneal dialysis : Dialysis that uses the lining of the abdomen as a membrane to remove waste and excess fluid. It is a home-based kidney replacement therapy that can compete with transplantation or bridge to it.
Xenotransplantation of kidneys : Transplantation of kidneys from nonhuman animals, especially genetically modified pigs, into humans. Animal organs could expand supply, but long-term safety and function remain unsettled.
Human leukocyte antigen : Cell-surface proteins that help the immune system distinguish the body's own cells from foreign tissue. HLA differences between donor and recipient influence rejection risk and matching.
Living donor kidney transplantation : Kidney transplantation using an organ donated by a living person, often a relative, friend, or altruistic donor. A living donor can make transplantation possible without waiting for a deceased-donor organ.
Delayed graft function : Slow recovery of a transplanted kidney, often requiring dialysis during the first week after surgery. The new kidney may not work immediately, particularly after deceased donation.
Hemodialysis : Dialysis that circulates blood through a filter to remove waste and excess fluid. It is the most familiar alternative for people awaiting or unable to receive a transplant.
Tolerance induction : Strategies intended to make the immune system accept a transplanted organ without continuous broad immunosuppression. True tolerance could reduce lifelong drug exposure and its complications.
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