Luteinizing hormone

Luteinizing hormone is a pituitary glycoprotein hormone that stimulates ovulation and corpus luteum formation in females and testosterone production in males.

Gonadotropin-releasing hormone: A hypothalamic peptide hormone that stimulates pituitary release of luteinizing hormone and follicle-stimulating hormone. Pulses of this hormone drive pituitary LH secretion.
Anterior pituitary: The front portion of the pituitary gland, which secretes hormones under hypothalamic control. Gonadotroph cells here release LH into the bloodstream.
Ovulation predictor kit: A home test that detects the rise in urinary luteinizing hormone before ovulation. It uses the LH surge to estimate the fertile window.
Testosterone: A steroid sex hormone produced mainly by the testes and, in smaller amounts, by other tissues. LH stimulates Leydig cells to produce this principal testicular androgen.
Luteinizing hormone receptor: A cell-surface G protein-coupled receptor activated by luteinizing hormone and human chorionic gonadotropin. LH produces its effects by activating this receptor on gonadal cells.
Gonadotropin: A hormone that acts on the gonads; in humans the principal examples are LH and FSH. LH belongs to this hormone family.
Luteinizing hormone assay: A laboratory test that measures luteinizing hormone in blood or urine. Measured LH helps assess reproductive function and guide treatment.
Progesterone: A steroid hormone that prepares and maintains the uterine lining for pregnancy. The corpus luteum formed under LH influence secretes progesterone.
LH surge: A brief, marked rise in luteinizing hormone secretion that precedes ovulation. This mid-cycle spike triggers the ovulatory cascade.
Glycoprotein hormone: A protein hormone bearing carbohydrate chains that can affect its stability and biological activity. LH shares a common glycoprotein structure with related reproductive hormones.

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