Knowra Methamphetamine Methamphetamine Methamphetamine is a synthetic central nervous system stimulant that increases alertness and energy. It has limited medical use and carries a high risk of dependence and serious health harms.
Dopamine transporter : A membrane protein that clears dopamine from the space between neurons by transporting it back into cells. Methamphetamine disrupts this transporter, contributing to elevated dopamine outside neurons.
Desoxyn : A prescription brand of methamphetamine hydrochloride approved in the United States for limited indications. It is the best-known example of methamphetamine’s tightly restricted medical use.
Methamphetamine-associated psychosis : A psychotic state linked to methamphetamine exposure, marked by symptoms such as paranoia or hallucinations. High-dose or prolonged exposure can trigger psychosis, sometimes persisting beyond intoxication.
Cocaine : A stimulant drug that blocks dopamine, norepinephrine, and serotonin reuptake and has local anesthetic properties. Both drugs can produce intense stimulation, but differ in duration, metabolism, and primary pharmacological actions.
Amphetamine synthesis : The chemical preparation of amphetamine, a stimulant first synthesized in the nineteenth century. Methamphetamine emerged from chemical modifications of the amphetamine structure.
Vesicular monoamine transporter 2 : A protein that moves monoamine neurotransmitters from the cell interior into storage vesicles. Methamphetamine interferes with vesicular storage, shifting dopamine into the neuron’s cytoplasm.
Attention deficit hyperactivity disorder : A neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity that impair functioning. Methamphetamine has a limited prescription role in treating ADHD when other options are unsuitable.
Stimulant-induced cardiomyopathy : Heart muscle disease caused or worsened by prolonged exposure to stimulant drugs. Methamphetamine can damage the heart and contribute to heart failure.
Methylphenidate : A prescription stimulant used mainly to treat ADHD and sometimes narcolepsy. It affects dopamine and norepinephrine transporters but is not the same compound or typical exposure as methamphetamine.
Akira Ogata : A Japanese chemist who reported a crystalline preparation of methamphetamine in 1919. Ogata’s method helped establish a form that was easier to handle and distribute.
Show all 28