Orthomyxoviridae

Orthomyxoviridae is a family of enveloped viruses with segmented, negative-sense RNA genomes. Its members include influenza viruses and infect vertebrates and other hosts.

Negative-sense RNA virus: A virus whose RNA genome must be transcribed into messenger RNA before it can direct protein production. Orthomyxoviridae genomes cannot serve directly as messenger RNA.
RNA virus: A virus whose genetic material is RNA rather than DNA. Every orthomyxovirus carries an RNA genome.
Influenza: A contagious respiratory illness caused by influenza viruses. Influenza viruses are the best-known disease-causing members of this family.
Influenzavirus A: A genus of influenza viruses infecting birds, mammals, and other hosts. Its broad host range and reassortment make it a major source of influenza outbreaks.
Zoonosis: An infectious disease transmitted between animals and humans. Some orthomyxoviruses cross from animal hosts into people.
Viral genome: The complete genetic material carried by a virus. Orthomyxoviridae package their genetic material in separate RNA segments.
Negative-sense RNA: RNA whose sequence is complementary to the messenger RNA used to make proteins. Orthomyxovirus genome segments are negative-sense RNA.
Influenza vaccine: A vaccine designed to induce immunity against influenza viruses. Vaccines target changing influenza strains to reduce illness and transmission.
Influenzavirus B: A genus of influenza viruses whose known natural hosts are humans and seals. It causes human seasonal influenza but has a narrower host range than Influenzavirus A.
Viral reassortment: The exchange of genome segments between viruses infecting the same cell. Reassortment can create orthomyxovirus strains with unfamiliar combinations of genes.

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Influenza A virusNarrower topic: Influenza A belongs to this family, distinguished in part by segmented genomes.