Knowra Pre-eclampsia Pre-eclampsia Pre-eclampsia is a pregnancy-related disorder involving new-onset high blood pressure after 20 weeks of gestation, often with proteinuria or other signs of organ dysfunction. It can threaten the health of both the pregnant person and fetus.
Placental development : The formation and growth of the placenta, including its attachment to the uterine wall and development of maternal blood supply. Abnormal early remodeling of uterine arteries is linked to many cases of pre-eclampsia.
Gestational hypertension : New-onset hypertension after 20 weeks of pregnancy without proteinuria or other diagnostic features of pre-eclampsia. It is distinguished from pre-eclampsia by the absence of qualifying proteinuria or organ dysfunction.
Maternal stroke : A sudden brain injury caused by interrupted blood flow or bleeding during pregnancy or the postpartum period. Severe hypertension in pre-eclampsia raises the risk of maternal stroke.
First pregnancy : A person's first pregnancy, regardless of its outcome. Pre-eclampsia occurs more often in first pregnancies than in many later pregnancies.
Preeclampsia screening : Methods used to estimate the likelihood that a pregnant person will develop pre-eclampsia. Screening strategies combine clinical risk factors and, in some settings, biomarkers or ultrasound.
Spiral artery remodeling : The transformation of uterine spiral arteries into wide, low-resistance vessels that supply the placenta. Incomplete remodeling can leave placental blood flow restricted in pre-eclampsia.
Proteinuria : An abnormal amount of protein in urine, which can indicate kidney involvement or other disease. It is one possible diagnostic feature, but pre-eclampsia can occur without it.
Acute kidney injury : A rapid decline in kidney function that causes waste products to accumulate in the blood. Pre-eclampsia can impair kidney function, sometimes severely.
Multiple pregnancy : A pregnancy involving two or more fetuses. Twins and higher-order pregnancies carry greater pre-eclampsia risk.
Preeclampsia biomarkers : Measurable biological features used to assess pre-eclampsia risk, diagnosis, or prognosis. Their best use for prediction and clinical decisions remains under study.
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