Knowra Resveratrol Resveratrol Resveratrol is a stilbenoid polyphenol produced by some plants and found in foods including grapes and peanuts. It is studied for effects on cellular signaling, inflammation, and metabolism.
Sirtuin 1 : Sirtuin 1 is an NAD+-dependent enzyme that regulates proteins through deacetylation and influences metabolism and stress responses. Resveratrol was proposed to activate this enzyme, though direct activation remains disputed.
Phytoalexin : A phytoalexin is an antimicrobial or defensive compound that plants produce in response to stress or infection. Resveratrol is produced as part of plant defense, especially after fungal attack or injury.
Red wine : Red wine is wine made by fermenting dark grape varieties with their skins, seeds, and sometimes stems. Resveratrol in grape skins helped motivate claims linking red wine to cardiovascular health.
Pterostilbene : Pterostilbene is a methylated stilbenoid found in blueberries and other plants, structurally related to resveratrol. Its chemical similarity invites comparisons, but differences in metabolism and evidence prevent treating the compounds as interchangeable.
Hormesis : Hormesis is a dose-response pattern in which a low exposure stimulates a response while a higher exposure inhibits or harms it. Resveratrol's effects can vary with dose, making simple claims about more being better unreliable.
AMP-activated protein kinase : AMP-activated protein kinase is a cellular energy sensor that adjusts metabolism when energy is scarce. Resveratrol can affect this pathway, which may mediate some metabolic effects.
Vitis vinifera : Vitis vinifera is the grapevine species cultivated for table grapes, raisins, and most wine grapes. Grapevines produce resveratrol, particularly in response to fungal disease and environmental stress.
Dietary supplement : A dietary supplement is a product intended to add nutrients or other substances to the diet. Resveratrol is sold in supplements, although product doses and formulations vary.
Quercetin : Quercetin is a flavonoid polyphenol found in many fruits, vegetables, and beverages. It is another widely studied dietary polyphenol, but belongs to a different structural family.
Pharmacokinetics : Pharmacokinetics describes how a substance is absorbed, distributed, metabolized, and eliminated by the body. Understanding resveratrol's exposure over time is essential for interpreting experiments and choosing human doses.
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