Knowra Semaglutide Semaglutide Semaglutide is a long-acting glucagon-like peptide-1 receptor agonist used to improve blood glucose control in type 2 diabetes and support chronic weight management.
GLP-1 receptor : A cell-surface receptor activated by glucagon-like peptide-1 and related medicines to regulate appetite and glucose metabolism. Semaglutide produces its effects by activating this receptor.
Type 2 diabetes : A chronic metabolic disease in which insulin resistance and impaired insulin production cause elevated blood glucose. Semaglutide is prescribed to improve glycemic control in this disease.
Tirzepatide : A once-weekly medicine that activates both glucose-dependent insulinotropic polypeptide and GLP-1 receptors. It targets two incretin receptors, unlike semaglutide's single-receptor action.
Gastrointestinal adverse effects of GLP-1 receptor agonists : Nausea, vomiting, diarrhea, constipation, and related digestive symptoms associated with GLP-1 receptor agonist treatment. These symptoms are common during semaglutide treatment, particularly during dose escalation.
Glucagon-like peptide-1 : A gut and brain signaling hormone that helps regulate blood glucose, appetite, and digestion. Semaglutide imitates this hormone while resisting rapid breakdown.
Obesity : A chronic disease characterized by excess body fat that can impair health. Semaglutide is used alongside reduced-calorie eating and increased activity for chronic weight management.
Liraglutide : A GLP-1 receptor agonist administered daily for diabetes or weight management, depending on formulation. It shares semaglutide's receptor target but generally requires daily injections.
Diabetic retinopathy : Damage to retinal blood vessels caused by diabetes, which can threaten vision. Rapid glucose improvement with semaglutide may worsen existing retinopathy in some patients.
Gastric emptying : The process by which stomach contents pass into the small intestine. Semaglutide slows this process, especially early in treatment.
Ozempic : A once-weekly injectable semaglutide product approved for adults with type 2 diabetes in several countries. This brand delivers semaglutide primarily for diabetes treatment.
Show all 22