The New England Journal of Medicine

The New England Journal of Medicine is a peer-reviewed medical journal published by the Massachusetts Medical Society. It publishes clinical research, reviews, and commentary.

Randomized controlled trial: A study that randomly assigns participants to interventions to compare their effects. Many clinical studies published in the journal use randomization to test treatments.
Massachusetts Medical Society: A professional organization representing physicians and other health professionals in Massachusetts. The society publishes the journal and has sustained its institutional identity.
Peer review: Evaluation of scholarly work by experts in the relevant field before publication. External expert assessment is one stage in evaluating submitted research.
Evidence-based medicine: The integration of research evidence, clinical expertise, and patient values in medical decisions. The journal helps circulate evidence used within this approach to care.
Systematic review: A structured synthesis of research that uses explicit methods to identify and assess relevant studies. The journal publishes reviews that consolidate evidence across clinical studies.
John Collins Warren: An American surgeon who helped found the Massachusetts General Hospital and served as its first surgeon. Warren founded the journal in 1812 as editor of its predecessor.
Editorial process: The procedures editors use to assess, revise, select, and prepare material for publication. Journal editors decide which submissions advance and how accepted work is presented.
Vioxx controversy: The public and scientific dispute over cardiovascular risks, marketing, and regulation of the painkiller rofecoxib. Journal-published research contributed to scrutiny of rofecoxib's cardiovascular safety.
Clinical practice guideline: A recommendation intended to help clinicians and patients choose appropriate care. Research reported in the journal can inform recommendations for clinical practice.
New England Journal of Medicine and Surgery: An early nineteenth-century medical periodical that preceded the New England Journal of Medicine. This predecessor began the publication lineage that became the journal.

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