Knowra Trisodium citrate Trisodium citrate Trisodium citrate is the sodium salt of citric acid. It binds calcium ions and is used as a food additive, a buffer, and an anticoagulant in blood collection and transfusion.
Food acidity regulator : A food additive that adjusts or stabilizes a product’s acidity. Trisodium citrate regulates acidity and contributes a salty, tart taste in foods and drinks.
Calcium chelation : The binding of calcium ions by molecules that coordinate the metal ion at multiple sites. Citrate binds calcium, reducing the free calcium needed for several steps in coagulation.
Sodium : A soft, highly reactive alkali metal whose ions are common in salts and biological fluids. Three sodium ions balance the charge of citrate in the fully neutralized salt.
Potassium citrate : A potassium salt of citric acid used in foods and medicine, including to alkalinize urine. It supplies potassium rather than sodium, changing its nutritional and medical uses.
Blood collection : The process of obtaining blood samples or donations for testing, storage, or transfusion. Trisodium citrate prevents collected blood from clotting by binding calcium.
Coagulation cascade : A sequence of reactions that forms fibrin and a blood clot. Many coagulation reactions require calcium, which citrate removes from the available pool.
Molecular formula : A notation that specifies the kinds and numbers of atoms in a molecule or formula unit. The anhydrous compound has formula Na₃C₆H₅O₇; commercial forms may include water of crystallization.
Sodium citrate : A sodium salt of citric acid, commonly used as a buffer, food additive, or anticoagulant. This broader name can include citrate salts with different sodium-to-citrate ratios.
Blood transfusion : The transfer of donated blood or blood components into a recipient’s circulation. Citrate anticoagulants help preserve blood components and limit clotting during storage and transfusion.
Buffer solution : A solution that resists changes in pH when small amounts of acid or base are added. Citrate participates in acid–base equilibria that let citrate-containing solutions buffer pH.
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