KnowraUracilUracilUracil is a pyrimidine nucleobase found in RNA, where it pairs with adenine. DNA generally uses thymine instead.BriefConnectPyrimidine: A class of nitrogen-containing heterocyclic compounds with a six-membered ring containing two nitrogen atoms. Uracil belongs to this chemical family.Hydrogen bond: An attractive interaction involving a hydrogen atom bonded to an electronegative atom and another electronegative atom. Hydrogen bonds help stabilize uracil–adenine pairs.Thymine: A pyrimidine nucleobase found mainly in DNA, where it pairs with adenine. DNA generally uses thymine where RNA uses uracil.Uracil-DNA glycosylase treatment: A laboratory procedure that uses uracil-DNA glycosylase to remove uracil-containing DNA molecules. It exploits uracil recognition to prevent carryover contamination in PCR.Robert Behrend: A German chemist who first prepared uracil in the nineteenth century. His chemical work produced uracil before its biological role was known.Nucleobase: A nitrogen-containing molecule that forms part of a nucleotide and carries genetic information in nucleic acids. Uracil is one of the bases used to build RNA.RNA transcription: The synthesis of RNA from a DNA template by an RNA polymerase. RNA polymerase incorporates uracil opposite adenine in the DNA template.DNA: A nucleic acid that stores hereditary information, usually as a double-stranded molecule containing thymine. Its use of thymine distinguishes DNA's standard base set from RNA's.Polymerase chain reaction: A laboratory method that amplifies selected DNA sequences through repeated cycles of synthesis and heating. Uracil-containing carryover products can be selectively destroyed before amplification.Albrecht Kossel: A German biochemist who investigated nucleic acids and their constituent bases, receiving the 1910 Nobel Prize in Physiology or Medicine. His studies helped establish the chemical identities of nucleic-acid bases.Show all 27Linked from 6 pagesCytosineCompared with: Uracil is cytosine’s deamination product and differs by lacking an amino group.Show all 6