Linked from

The 39 pages that link to Alzheimer's disease, each with the reason it gives.

• Protein foldingBroader topic: Amyloid-beta and tau protein assemblies are hallmarks of its pathology.

• Cerebrospinal fluidRelated: Fluid levels of amyloid and tau-related biomarkers can inform its evaluation.

• SynapseRelated: Synaptic dysfunction and loss are closely associated with cognitive impairment in the disease.

• NeurodegenerationBroader topic: It is a common example of neurodegeneration, especially affecting memory-related brain systems.

• NeuroinflammationRelated: Microglial and cytokine responses accompany disease pathology and may affect its progression.

• PrionCompared with: Its proteins can spread between cells, but typical Alzheimer's is not an infectious prion disease.

• Synaptic plasticityRelated: Impaired synaptic function is closely associated with early cognitive deficits.

• Episodic memoryRelated: Difficulty forming new episodic memories is often an early symptom.

• AstrocyteRelated: Astrocytes respond to amyloid and neuronal injury, and their functions change during disease progression.

• Protein misfoldingBroader topic: Amyloid-beta and tau misfolding and aggregation are central features of its pathology.

• AmyloidBroader topic: Amyloid-β deposits are a defining pathological feature, though they do not alone explain the disease.

• AnosmiaRelated: Impaired odor identification can accompany neurodegeneration, though it is not diagnostic alone.

• Default mode networkRelated: Network hubs are affected by disease-related changes and help researchers study early dysfunction.

• Gray matterRelated: Disease-related brain atrophy can include loss of gray-matter volume in affected regions.

• Acetylcholinesterase inhibitorRelated: Several inhibitors are used to lessen cognitive symptoms, though they do not stop disease progression.

• Locus coeruleusRelated: Locus-coeruleus degeneration can occur early and may affect brain-wide norepinephrine signaling.

• Frontotemporal dementiaCompared with: Early memory impairment is more typical here than in many frontotemporal presentations.

• Chronic traumatic encephalopathyCompared with: Both diseases involve tau pathology, but they have different defining patterns and associated features.

• Dementia with Lewy bodiesCompared with: Its typical memory-led course differs from the early hallucinations and fluctuations often seen here.

• Rita HayworthRelated: Hayworth's diagnosis later drew public attention to the disease and its effects.

• Tau proteinBroader topic: Tau tangles track neuronal injury and disease progression in Alzheimer disease.

• DendriteRelated: Alzheimer's disease is associated with synapse loss and alterations in dendritic spines.

• Dissociative amnesiaCompared with: Progressive cognitive decline points toward a neurological disorder rather than dissociative amnesia.

• Gene WilderRelated: Wilder’s family disclosed his diagnosis after his death to protect his privacy.

• Rita Levi-MontalciniRelated: Levi-Montalcini’s work helped prompt research into growth factors and neuronal loss in this disease.

• The NotebookRelated: The film’s memory-loss storyline is often discussed in relation to Alzheimer’s, though it does not clearly name a diagnosis.

• Corticobasal degenerationCompared with: Both involve tau, but their characteristic lesions and clinical patterns differ.

• Pat SummittRelated: Summitt announced her diagnosis in 2011 while continuing to coach that season.

• Alois AlzheimerBroader topic: The disorder was named after Alzheimer following his report on Auguste Deter.

• DonepezilRelated: Donepezil is prescribed to manage cognitive and functional symptoms of this disease.

• Glen CampbellRelated: Campbell was diagnosed in 2011 and continued performing during the early stages.

• Transmissible spongiform encephalopathyCompared with: Both involve abnormal protein aggregation, but Alzheimer’s disease is not ordinarily transmissible between hosts.

• May-Britt MoserRelated: Early damage to entorhinal regions makes navigation deficits a focus of disease research.

• Neurodegenerative diseaseBroader topic: It is a common example of degeneration centered on memory and cognition.

• Pick's diseaseCompared with: Both can impair cognition, but Alzheimer's disease has different defining protein pathology.

• Ramón Villeda MoralesRelated: Research on aging-related blood signals intersects with questions about vulnerability to neurodegeneration.

• Amaryllidaceae alkaloidsRelated: Galantamine is prescribed to alleviate some cognitive symptoms of this disease.

• Emilia ClarkeRelated: Clarke has supported Alzheimer’s research through public fundraising and advocacy.

• Nervous System DiseasesBroader topic: It demonstrates how neurodegeneration can progressively impair memory and thinking.