KnowraAntimetaboliteLinked fromLinked fromThe 11 pages that link to Antimetabolite, each with the reason it gives.All 11Broader topic 3Related 2Narrower topic 5Compared with 1ChemotherapyBroader topic: Their false building blocks disrupt the replication that rapidly dividing cancer cells require.PyrimidineNarrower topic: Several drugs mimic pyrimidines or block their synthesis to restrain cell growth.Alkylating agentCompared with: Antimetabolites interfere with nucleotide pathways rather than directly transferring alkyl groups to DNA.Immunosuppressive therapyBroader topic: They reduce expansion of activated lymphocytes by restricting cell growth.Guanosine triphosphateRelated: Some antimetabolite drugs inhibit nucleotide synthesis, reducing GTP available to proliferating cells.AntifungalNarrower topic: Flucytosine works as an antifungal after fungal cells convert it into antimetabolites.Immunosuppressive drugBroader topic: Mycophenolate and azathioprine limit the proliferation of immune cells.Gerhard DomagkRelated: Sulfonamides mimic para-aminobenzoic acid and thereby interrupt bacterial folate synthesis.Gertrude B. ElionNarrower topic: Several of Elion’s medicines mimic purines or folate-related compounds to interrupt cell growth.MercaptopurineNarrower topic: This drug class describes how mercaptopurine interferes with purine-dependent cellular processes.FluorouracilNarrower topic: This drug class captures how fluorouracil impersonates pyrimidine metabolites.