Linked from

The 13 pages that link to Beta-lactam ring, each with the reason it gives.

• PenicillinBroader topic: This ring lets penicillin mimic a cell-wall building block and bind its target enzymes.

• Beta-lactam antibioticBroader topic: This structural feature enables covalent inhibition of penicillin-binding proteins.

• Beta-lactamaseBroader topic: Its hydrolysis is the defining reaction that lets beta-lactamases inactivate susceptible drugs.

• AmoxicillinBroader topic: This strained ring enables amoxicillin to inactivate its bacterial enzyme targets.

• CephalosporinBroader topic: This reactive ring enables cephalosporins to bind their bacterial enzyme targets.

• CarbapenemBroader topic: This strained ring enables carbapenems to inhibit cell-wall enzymes.

• Extended-spectrum beta-lactamaseBroader topic: ESBLs hydrolyze this structure, disabling the antibiotics they target.

• CefiximeBroader topic: This ring lets cefixime acylate its target enzymes and block their activity.

• Clavulanic acidBroader topic: Its strained ring helps clavulanic acid react with beta-lactamase.

• FlucloxacillinRelated: Its intact ring is essential to flucloxacillin’s activity against bacterial targets.

• BenzylpenicillinBroader topic: Its reactive structure lets benzylpenicillin mimic a substrate recognized by cell-wall enzymes.

• AmpicillinBroader topic: This strained ring reacts with target enzymes and is essential to ampicillin’s activity.

• CloxacillinRelated: Cloxacillin’s antibacterial action depends on this ring remaining intact until it reaches its target.