Candida albicans

Candida albicans is a yeast species that commonly inhabits human skin and mucosal surfaces. It can cause infections when host defenses or microbial balance are disrupted.

Hyphal transition: The change of a yeast cell into an elongated filamentous form. Filament formation helps C. albicans invade tissue and damage host cells.
Oral candidiasis: A Candida infection of the mouth, often producing white patches or red, sore areas. C. albicans is a common cause, especially when local or immune defenses are impaired.
Yeast: A single-celled fungus that reproduces primarily by budding or fission. C. albicans grows as yeast cells as well as filamentous forms.
Candida glabrata: A Candida yeast species that causes mucosal and invasive infections, often with reduced antifungal susceptibility. It is a common non-albicans cause of candidiasis and differs in morphology and treatment response.
Antifungal resistance: The ability of a fungus to survive or grow despite exposure to antifungal drugs. Resistance in C. albicans can complicate treatment, particularly after repeated drug exposure.
Candida albicans biofilm: A structured community of C. albicans cells embedded in a self-produced matrix. Biofilms on medical devices resist antifungal drugs and immune clearance.
Vulvovaginal candidiasis: Inflammation of the vulva and vagina caused by overgrowth of Candida species. C. albicans causes most uncomplicated cases.
Dimorphic fungi: Fungi capable of growing in two distinct forms, often in response to environmental conditions. C. albicans is polymorphic, with yeast and filamentous growth states.
Candida tropicalis: A Candida species that causes bloodstream and other invasive infections, particularly in immunocompromised people. It is another clinically important Candida pathogen, especially in some regions and patient groups.
Candida albicans sexual reproduction: The mating and genetic recombination processes available to Candida albicans. Its unusual mating biology raises questions about how recombination contributes to adaptation.

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