Linked from

The 10 pages that link to Chromosomal translocation, each with the reason it gives.

• MutationBroader topic: Large-scale rearrangements can alter many genes at once.

• ChromosomeRelated: Some translocations cause disease or provide diagnostic markers.

• Genetic recombinationBroader topic: Some translocations arise through recombination between inappropriate DNA sites.

• Multiple myelomaRelated: Certain translocations activate growth-promoting genes in myeloma cells.

• Chromosome theory of inheritanceRelated: Translocations can disrupt genes or change their inheritance context.

• Non-homologous end joiningRelated: Misjoining unrelated broken ends can create translocations.

• CytogeneticsBroader topic: Balanced and unbalanced translocations can affect fertility, development, or cancer biology.

• Burkitt lymphomaRelated: The identification of recurrent chromosome translocations linked the disease to MYC dysregulation.

• SarcomaRelated: Some sarcomas are driven by translocations that create abnormal fusion genes.

• Chromosome abnormalityBroader topic: Translocations can disrupt genes or alter their regulation and inheritance.