Linked from

The 27 pages that link to DNA polymerase, each with the reason it gives.

• Polymerase chain reactionRelated: During extension, polymerase copies each template from its bound primer.

• DNABroader topic: It performs the nucleotide-by-nucleotide synthesis central to DNA copying.

• EnzymeBroader topic: Its copying activity underlies DNA replication and many laboratory methods.

• DNA sequencingRelated: Polymerase-driven synthesis underlies sequencing-by-synthesis methods.

• DNA replicationRelated: It builds new DNA strands by matching nucleotides to parental templates.

• DNA repairRelated: Repair synthesis uses polymerases to replace nucleotides removed or lost during repair.

• Single-nucleotide polymorphismRelated: Polymerase errors can insert a wrong nucleotide during DNA copying.

• Frederick SangerRelated: Sanger sequencing relies on DNA polymerase to build fragments that reveal base order.

• DNA ligaseRelated: Polymerase fills many gaps; ligase then seals the remaining nick.

• Phosphodiester bondRelated: It forms phosphodiester bonds while extending DNA in the 5′-to-3′ direction.

• RNA polymeraseCompared with: Unlike RNA polymerase, it builds DNA rather than RNA and generally requires a primer.

• DeoxyriboseRelated: These enzymes select and join deoxyribose-containing DNA building blocks.

• Reverse transcriptionNarrower topic: Reverse transcriptase is a specialized DNA polymerase with an RNA template.

• CytarabineRelated: Cytarabine triphosphate competes at these enzymes and impairs DNA-chain elongation.

• Sanger sequencingRelated: It copies the template and incorporates ordinary or chain-terminating nucleotides.

• Site-directed mutagenesisRelated: The polymerase copies the target region and can carry the primer-encoded change into new DNA.

• Magnesium ionRelated: Many DNA polymerases use Mg²⁺ ions to position substrates and catalyze phosphodiester-bond formation.

• Taq polymeraseNarrower topic: Taq is one specialized member of this enzyme family.

• TelomeraseCompared with: Unlike conventional DNA polymerases, telomerase carries its own RNA template.

• Thermus aquaticusNarrower topic: Taq polymerase is one specialized member of this enzyme family.

• ThymidineRelated: DNA polymerases incorporate thymidine triphosphate opposite adenine.

• Kary MullisRelated: PCR depends on this enzyme to extend primers and copy DNA.

• Point mutationRelated: Its occasional copying errors can introduce mismatched nucleotides.

• Severo OchoaCompared with: Kornberg’s DNA-synthesizing enzyme provided the DNA counterpart to Ochoa’s RNA work.

• SulfolobusRelated: Thermostable polymerases from related archaea support high-temperature DNA amplification and sequencing.

• ThermoproteotaRelated: Thermostable polymerases from hot-environment archaea support high-temperature DNA amplification.

• Tsuneko OkazakiRelated: Their directional synthesis makes discontinuous copying of the lagging strand necessary.