Linked from

The 45 pages that link to Drug discovery, each with the reason it gives.

• Stem cellRelated: Stem-cell-derived cells can be used to test drug effects and toxicity in human-like cell types.

• Animal testingRelated: Animal studies may test candidate drugs' effects and risks before human trials.

• OrganoidRelated: Organoid assays can compare candidate compounds in tissue-like cultures.

• BioinformaticsRelated: Computational screening and molecular modeling can prioritize candidate compounds.

• Click chemistryRelated: Modular click assembly lets chemists rapidly build and test collections of candidate molecules.

• Pharmaceutical industryBroader topic: It begins the industry's search for medicines with useful biological effects.

• Embryonic stem cellRelated: Stem-cell-derived cells can be used to test drug effects and toxicity.

• Protein structure predictionRelated: Predicted target structures can guide binding-site analysis and early compound design.

• ChemoselectivityNarrower topic: Chemoselective synthesis enables efficient preparation and modification of candidate molecules.

• Cryo-electron microscopyRelated: Cryo-EM structures can reveal binding sites and guide medicinal chemistry.

• PharmacognosyNarrower topic: Natural-source research has supplied drug leads and compounds for therapeutic development.

• Enzyme assayRelated: Assays identify compounds that inhibit or otherwise alter target enzyme activity.

• Induced pluripotent stem cellRelated: Reprogrammed patient cells can help test candidate drugs in disease-relevant human cells.

• Drug targetNarrower topic: Target choice helps shape screening strategies and the design of candidate medicines.

• Active pharmaceutical ingredientNarrower topic: Drug discovery identifies candidate substances that may become APIs.

• Drug designNarrower topic: Drug design is one stage in this broader search for useful medicines.

• Natural productRelated: Natural products provide biologically active starting points for finding medicines.

• Materia medicaRelated: Modern discovery tests and extends the search for therapeutically useful substances.

• TerpenoidRelated: Terpenoid diversity continues to prompt searches for new therapeutic compounds and mechanisms.

• Drug developmentBroader topic: It generates and evaluates candidate medicines before formal development begins.

• Merck & Co.Narrower topic: Merck's research begins by finding and testing potential medicines and vaccines.

• Chemical Abstracts ServiceRelated: Researchers use chemical databases to find compounds, prior art, and related literature.

• Structure–activity relationshipNarrower topic: Structure–activity analysis helps move early hits toward useful drug candidates.

• AlphaFoldRelated: Protein models can inform hypotheses about drug targets and binding sites.

• Positive allosteric modulatorRelated: Allosteric sites offer drug targets distinct from highly conserved orthosteric sites.

• Venom researchNarrower topic: Venom screening is a source of candidate molecules for drug discovery.

• Biomedical researchRelated: Biomedical research reveals targets and candidate compounds for new medicines.

• Chemical biologyRelated: Chemical biology helps validate targets and explain how candidate drugs act.

• BiomoleculeRelated: Drug discovery often targets biomolecules or uses them to identify disease mechanisms.

• Bristol Myers SquibbNarrower topic: It begins the path from biological insight to a potential company medicine.

• James BlackNarrower topic: Black’s research linked physiological hypotheses to deliberately designed medicines.

• Shinya YamanakaRelated: Patient-specific induced pluripotent cells provide human cell models for testing candidate drugs.

• Taxus brevifoliaNarrower topic: Paclitaxel’s path from yew bark to medicine exemplifies natural-product drug discovery.

• Computational biologyRelated: Computational analysis helps prioritize targets, screen compounds, and estimate molecular interactions.

• Gila monsterNarrower topic: Its saliva illustrates how studying animal molecules can yield medicines.

• William C. CampbellNarrower topic: Campbell’s screening and development work turned a natural compound into a usable medicine.

• Brian KobilkaNarrower topic: GPCR research matters partly because these receptors are major drug targets.

• MedicineNarrower topic: It begins the long path from biological target to potential treatment.

• Ben FeringaRelated: Asymmetric catalysis can provide stereochemically defined compounds relevant to medicinal chemistry.

• Combinatorial chemistryNarrower topic: Finding candidate molecules is a major use of combinatorial libraries.

• EnzymologyRelated: Enzyme assays and inhibitor studies help identify and refine drug candidates.

• Gertrude B. ElionNarrower topic: Elion’s work showed how biochemical knowledge could guide the search for useful medicines.

• Amaryllidaceae alkaloidsRelated: Amaryllidaceae alkaloids provide natural scaffolds and biological leads for this research.

• Erwin NeherRelated: Patch-clamp assays test whether candidate drugs alter ion-channel activity.

• Organ printingRelated: Printed tissues can provide human-cell models for testing drug effects and toxicity.