Linked from

The 15 pages that link to Duchenne muscular dystrophy, each with the reason it gives.

• X-linked inheritanceBroader topic: Its usual inheritance is X-linked recessive, with symptoms typically beginning in childhood.

• X chromosomeBroader topic: The dystrophin gene is X-linked, so inheritance follows characteristic sex-dependent patterns.

• Muscle weaknessBroader topic: It illustrates weakness caused by structural damage within muscle fibers.

• X-linked recessive inheritanceBroader topic: Its usual X-linked inheritance makes it a prominent example of affected boys and carrier females.

• Muscular dystrophyBroader topic: It is a prominent childhood-onset form with progressive weakness and loss of mobility.

• RNA splicingRelated: Some treatments alter splicing to restore the reading frame in selected DMD transcripts.

• Sex-linked inheritanceBroader topic: Variants in the X-linked DMD gene produce a well-studied recessive inheritance pattern.

• Spinal muscular atrophyCompared with: It causes progressive weakness through primary muscle damage rather than spinal motor-neuron loss.

• Congenital myopathyCompared with: Its progressive dystrophic course differs from many congenital myopathies, which are relatively stable.

• ExonBroader topic: Exon-skipping therapies target dystrophin exons to help restore its reading frame.

• MyopathyBroader topic: It exemplifies a severe inherited myopathy caused by a defined structural-protein defect.

• SarcolemmaBroader topic: Dystrophin loss destabilizes the muscle-fiber membrane during repeated contraction.

• Becker muscular dystrophyCompared with: Both disorders involve DMD, but Becker muscular dystrophy usually begins later and progresses more slowly.

• Sex linkageRelated: The DMD gene's X-linked inheritance gives this disorder a characteristic family pattern.

• Mark R. HughesRelated: Hughes helped identify the gene responsible, enabling direct genetic diagnosis.