KnowraExtended-spectrum beta-lactamaseLinked fromLinked fromThe 10 pages that link to Extended-spectrum beta-lactamase, each with the reason it gives.All 10Broader topic 6Related 4Horizontal gene transferBroader topic: Genes for these enzymes often travel on plasmids between bacteria.Beta-lactamaseBroader topic: Detecting these enzymes helps explain resistance to commonly used cephalosporins.Beta-lactam ringBroader topic: Its spread challenges the design of ring variants intended to evade hydrolysis.CephalosporinRelated: ESBL production is a major cause of resistance to commonly used cephalosporins.CeftriaxoneBroader topic: ESBL production commonly makes an infection unsuitable for ceftriaxone treatment.CeftazidimeBroader topic: ESBL-producing bacteria commonly resist ceftazidime and related cephalosporins.CefiximeBroader topic: ESBL-producing bacteria are commonly resistant to cefixime.Clavulanic acidRelated: Clavulanate inhibits some enzymes in this group, but not reliably enough for every infection.CefotaximeRelated: These enzymes can inactivate cefotaxime and cause treatment resistance.MeropenemRelated: Carbapenems such as meropenem are often active against ESBL-producing bacteria, if susceptibility is retained.