KnowraHirschsprung diseaseLinked fromLinked fromThe 5 pages that link to Hirschsprung disease, each with the reason it gives.All 5Related 5Enteric nervous systemRelated: The missing neurons prevent normal relaxation and movement in the affected bowel segment.Neural crestRelated: Impaired migration or development of enteric neural crest cells can leave bowel segments without ganglia.Anorectal manometryRelated: Absence of the rectoanal inhibitory reflex can support evaluation, though biopsy establishes diagnosis.Waardenburg syndromeRelated: It can accompany Waardenburg syndrome type 4 when enteric nervous system development is disrupted.Central hypoventilation syndromeRelated: It can occur with congenital central hypoventilation as part of a broader autonomic disorder.