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The 37 pages that link to Hypothalamic–pituitary–adrenal axis, each with the reason it gives.
Post-traumatic stress disorderRelated: Stress-hormone regulation is studied as part of PTSD biology.
DepressionRelated: Stress-related hormonal regulation is one biological pathway studied in depression.
Major depressive disorderRelated: Stress-system changes are studied as one possible biological pathway involved in depression.
AnxietyRelated: Its activation can sustain physical arousal when a threat feels imminent.
CorticosteroidRelated: It controls the body's production of cortisol, a natural glucocorticoid.
Anxiety disorderRelated: Stress physiology can accompany anxiety, but no single hormonal pathway explains all anxiety disorders.
CortisolNarrower topic: This axis controls cortisol production through signals from the brain to the adrenal cortex.
Cushing syndromeNarrower topic: Its feedback controls cortisol secretion and is disrupted differently across syndrome causes.
Stress responseRelated: Its cortisol release sustains part of the response beyond the initial neural surge.
Adrenal insufficiencyNarrower topic: Disruption at any point in this axis can reduce cortisol activity.
Adverse childhood experiencesRelated: Studies investigate whether adversity alters this system's regulation over time.
DexamethasoneRelated: Dexamethasone suppresses this axis through negative feedback, especially with sustained use.
Adrenal cortexRelated: CRH and ACTH relay stress and circadian signals to cortisol-producing cortical cells.
PrednisoneRelated: Prolonged prednisone exposure can suppress this system through feedback.
Topical corticosteroidRelated: Extensive or prolonged absorption can suppress this system, particularly in children.
GlucocorticoidRelated: It controls the release of the body’s principal glucocorticoid, cortisol.
StressBroader topic: It sustains hormonal responses to stress through the release of cortisol.
Adrenocorticotropic hormoneNarrower topic: ACTH is the pituitary relay between hypothalamic CRH and adrenal responses.
HydrocortisoneRelated: Hydrocortisone can suppress this system’s signals and reduce endogenous cortisol production.
Psychosomatic medicineBroader topic: It is one pathway through which psychological stress can influence bodily processes.
Adrenal glandRelated: This feedback circuit controls cortisol release during stress and across the day.
Gut-brain axisRelated: Stress hormones alter gut function, while gut signals can influence stress responses.
Hypothalamic-pituitary axisBroader topic: It is the axis’s best-known route for coordinating hormonal stress responses.
Limbic systemRelated: It carries limbic influences into prolonged hormonal responses to stress.
Glucocorticoid withdrawalNarrower topic: Sustained glucocorticoid exposure suppresses this system, limiting the body's cortisol response after treatment stops.
Major depressive episodeRelated: Stress-system activity is studied as one possible contributor to depressive symptoms.
Mood disorderRelated: Stress-system activity is studied as one pathway related to depression.
Psychological stressRelated: It coordinates hormonal responses to perceived stressors, including cortisol release.
Acute stress reactionRelated: Its stress-hormone signaling contributes to the body's response after a threatening event.
CortisoneRelated: This system controls the body’s production of cortisol and related corticosteroids.
NeuroendocrinologyBroader topic: Its feedback loop links stress-related brain activity to cortisol release.
BetamethasoneRelated: Systemic betamethasone can suppress this axis and reduce the body's own cortisol production.
Cyclic vomiting syndromeRelated: Stress can trigger episodes, and stress-response pathways are studied as possible mechanisms.
Postpartum depressionRelated: Stress-system changes around childbirth may interact with susceptibility to depression.
PrednisoloneRelated: Prolonged prednisolone treatment can suppress this system and reduce natural cortisol production.
DehydroepiandrosteroneRelated: ACTH from this axis stimulates adrenal steroid production, including DHEA.
CorticosteroneNarrower topic: This axis stimulates adrenal corticosterone release and adjusts it through feedback.