KnowraIsofluraneLinked fromLinked fromThe 4 pages that link to Isoflurane, each with the reason it gives.All 4Broader topic 2Compared with 2SevofluraneCompared with: Isoflurane is less soluble than some older agents but generally less rapidly adjustable than sevoflurane.HalothaneCompared with: Isoflurane and other newer agents displaced halothane in many settings because of safety concerns.