KnowraLesch–Nyhan syndromeLinked fromLinked fromThe 4 pages that link to Lesch–Nyhan syndrome, each with the reason it gives.All 4Broader topic 3Related 1X-linked inheritanceBroader topic: It is a classic severe condition inherited through an X-linked recessive pattern.Purine metabolismBroader topic: Failure of purine salvage drives excess uric acid production and characteristic neurological symptoms.AllopurinolBroader topic: Allopurinol can treat its excess uric acid, but not its neurologic features.HypoxanthineRelated: Impaired hypoxanthine salvage contributes to excess uric acid and neurological symptoms.