KnowraLocus coeruleusLinked fromLinked fromThe 9 pages that link to Locus coeruleus, each with the reason it gives.All 9Broader topic 6Related 3ArousalBroader topic: Its norepinephrine signals help adjust alertness and responses to salient events.Norepinephrine transporterBroader topic: NET on locus coeruleus projections helps regulate norepinephrine signaling throughout the brain.Descending pain modulationBroader topic: Noradrenergic projections from this nucleus can suppress spinal nociceptive transmission.Opioid withdrawalBroader topic: Its heightened activity contributes to autonomic symptoms during withdrawal.PonsBroader topic: Its activity links this brainstem region to arousal and sleep-wake regulation.WakefulnessBroader topic: Its activity helps tune arousal during wakefulness.