Linked from

The 29 pages that link to Macrolide, each with the reason it gives.

• RibosomeBroader topic: Macrolides obstruct translation through a binding site in the large subunit.

• Beta-lactam antibioticCompared with: Macrolides target ribosomes rather than penicillin-binding proteins.

• AminoglycosideCompared with: Macrolides target the other major ribosomal subunit and have different resistance patterns.

• TetracyclineCompared with: Macrolides also target translation but bind a different ribosomal subunit.

• AzithromycinNarrower topic: Azithromycin belongs to this antibiotic class.

• CephalosporinCompared with: Macrolides target ribosomes rather than cell-wall enzymes, offering a different treatment class.

• StreptomycinCompared with: Macrolides target the other ribosomal subunit.

• Bacterial ribosomeRelated: Many macrolides obstruct the nascent peptide exit tunnel.

• ClindamycinCompared with: Macrolides bind a nearby ribosomal site, and shared resistance mechanisms can affect clindamycin activity.

• 50S ribosomal subunitRelated: Macrolides bind within the 50S exit tunnel and obstruct protein synthesis.

• ChloramphenicolCompared with: They target the same subunit but generally obstruct translation through different binding interactions.

• ErythromycinNarrower topic: Erythromycin is the prototype natural member of this antibiotic family.

• MycoplasmaRelated: They are used against susceptible respiratory Mycoplasma, whose lack of a cell wall rules out beta-lactams.

• Protein synthesis inhibitorBroader topic: Macrolides obstruct ribosomal movement and peptide-chain progression through a distinct binding site.

• FluoroquinoloneCompared with: Macrolides target translation, a distinct process from the DNA enzymes inhibited by fluoroquinolones.

• Bacteriostatic agentBroader topic: Macrolides commonly suppress growth through a different ribosomal target.

• Bacterial protein synthesisRelated: Macrolides interfere with elongation on bacterial ribosomes.

• Mycoplasma pneumoniaeRelated: Macrolides are commonly used against this bacterium, especially in children.

• Ada YonathBroader topic: Structures help locate macrolide binding sites and explain resistance mechanisms.

• ClarithromycinNarrower topic: Clarithromycin belongs to this antibiotic family and shares its ribosomal mode of action.

• Tetracycline antibioticsCompared with: Macrolides target a different ribosomal subunit and often offer an alternative for similar infections.

• Thomas A. SteitzBroader topic: Steitz’s structural work helped locate how macrolides bind within the large subunit.

• Whooping coughRelated: Macrolides are commonly used to treat pertussis and reduce contagiousness.

• Bordetella pertussisRelated: Macrolides are used to treat pertussis and reduce transmission when given early.

• Chlamydia pneumoniaeRelated: Macrolides are among the antibiotics used to treat suspected or confirmed C. pneumoniae respiratory infection.

• CefuroximeCompared with: Macrolides act on ribosomes rather than cell-wall synthesis, offering a mechanistically distinct alternative.

• NatamycinRelated: Natamycin has a macrolide ring as part of its chemical structure.

• OxytetracyclineCompared with: Macrolides share a broad therapeutic role but bind a different ribosomal target.

• PhenoxymethylpenicillinCompared with: Macrolides provide a non-beta-lactam alternative when penicillin cannot be used, subject to susceptibility.