KnowraMitochondrial diseaseLinked fromLinked fromThe 24 pages that link to Mitochondrial disease, each with the reason it gives.All 24Broader topic 3Related 11Narrower topic 4Compared with 6Mitochondrial DNARelated: Mutations in this genome can disrupt energy-producing mitochondrial proteins.Aerobic respirationRelated: Respiratory-chain defects can limit ATP production and disrupt tissues with high energy demands.Mitochondrial inheritanceRelated: Inheritance patterns help assess how mitochondrial variants may pass within families.HeteroplasmyRelated: A pathogenic mitochondrial variant can cause disease when its proportion is sufficiently high.UbiquinoneRelated: Defects in ubiquinone synthesis can disrupt mitochondrial energy production.MyopathyRelated: Energy failure can particularly affect muscle, which has high and fluctuating energy demands.Flavin mononucleotideRelated: Defects in FMN-dependent respiratory machinery can compromise mitochondrial energy generation.John E. WalkerRelated: Understanding ATP synthase structure supports investigation of mutations that disrupt mitochondrial energy production.LethargyRelated: Disrupted energy production can contribute to weakness and reduced activity.Extranuclear inheritanceRelated: Maternal transmission and heteroplasmy shape the inheritance and severity of some cases.MitochondriaRelated: Defects in mitochondrial genes or proteins can disrupt energy production and other functions.