Linked from

The 25 pages that link to Organophosphate poisoning, each with the reason it gives.

• ToxicologyBroader topic: It is a specific, well-characterized example of a toxicant acting through a molecular target.

• AcetylcholineRelated: Acetylcholine accumulates when its breakdown is inhibited, disrupting nerves, muscles, and glands.

• Neuromuscular junctionRelated: Blocking acetylcholine breakdown overstimulates neuromuscular junctions.

• AtropineRelated: Atropine treats dangerous muscarinic symptoms such as bronchial secretions and bronchoconstriction.

• AcetylcholinesteraseRelated: Organophosphates can phosphorylate the enzyme and prevent it from clearing acetylcholine.

• Parasympathetic nervous systemRelated: Excess acetylcholine can produce severe overstimulation of parasympathetic targets.

• Botulinum toxinCompared with: It produces excessive cholinergic signaling, opposite the toxin’s blockade of acetylcholine release.

• NeurotoxinBroader topic: It illustrates how a shared molecular target can produce severe nervous-system effects.

• NeurotoxicityBroader topic: The acute syndrome illustrates neurotoxicity through excessive acetylcholine signaling.

• PralidoximeRelated: This is the poisoning mechanism pralidoxime is intended to counter.

• BotulismCompared with: It disrupts cholinergic signaling in the opposite direction from botulinum toxin.

• Cholinergic crisisBroader topic: It is a major cause of acute cholinergic crisis after pesticide exposure or nerve-agent exposure.

• Enzyme inhibitionRelated: It demonstrates the physiological consequences of persistent enzyme inhibition.

• PoisoningBroader topic: Its characteristic cholinergic effects illustrate poisoning through a specific molecular target.

• Acetylcholinesterase inhibitorBroader topic: Many organophosphates produce severe toxicity by inhibiting the same enzyme.

• Nerve agentCompared with: It shares the enzyme-inhibition mechanism but includes non-weapon exposures.

• SarinNarrower topic: Sarin poisoning is an extreme, weaponized form of this broader toxicological syndrome.

• AntidoteRelated: Atropine and pralidoxime address different consequences of this poisoning.

• Tokyo subway sarin attackNarrower topic: Sarin casualties required clinicians to recognize and treat a mass episode of this poisoning.

• Synaptic cleftRelated: Inhibition prevents acetylcholine clearance from synaptic clefts.

• Atropa belladonnaCompared with: Atropine treats its muscarinic symptoms, despite belladonna alkaloids causing the opposite receptor effect.

• MalathionNarrower topic: Excessive malathion exposure can produce this broader toxic syndrome.

• SomanNarrower topic: Soman is one cause of this broader poisoning syndrome.

• MuscarineCompared with: Both can cause muscarinic symptoms, but organophosphates raise endogenous acetylcholine rather than directly mimicking it.

• Tetraethyl pyrophosphateNarrower topic: This broader toxicological syndrome includes exposure to tetraethyl pyrophosphate.