Linked from

The 13 pages that link to Tumor necrosis factor, each with the reason it gives.

• CytokineBroader topic: This family includes potent inflammatory signals and therapeutic targets.

• PsoriasisRelated: It is one of the inflammatory signals targeted by psoriasis medicines.

• ThalidomideRelated: Thalidomide can suppress tumor necrosis factor production, contributing to its anti-inflammatory effects.

• Crohn's diseaseRelated: Several effective Crohn's treatments block this inflammatory signal.

• GranulomaRelated: TNF helps maintain granuloma organization; blocking it can allow latent infections to reactivate.

• Cytokine stormBroader topic: It can contribute to vascular and tissue injury when inflammatory signaling becomes excessive.

• Psoriatic arthritisRelated: TNF is one inflammatory pathway targeted by effective treatments.

• InterferonCompared with: Its inflammatory and cell-death effects contrast with interferons' signature antiviral gene programs.

• Ankylosing spondylitisRelated: TNF signaling contributes to inflammation and is a target of established treatment.

• SarcoidosisRelated: Tumor necrosis factor helps sustain granulomatous inflammation and is targeted by some treatments.

• Bruce BeutlerRelated: Beutler’s earlier endotoxin research showed how this cytokine mediates toxic effects of bacterial products.

• Jarisch–Herxheimer reactionRelated: Its rise during the reaction helps explain the acute fever and systemic inflammation.

• CherubismRelated: Increased inflammatory signaling involving this cytokine is implicated in cherubism lesions.