KnowraVariolationLinked fromLinked fromThe 6 pages that link to Variolation, each with the reason it gives.All 6Related 3Narrower topic 1Compared with 2VaccinationNarrower topic: Variolation preceded vaccination but carried a greater risk of severe disease and transmission.VaccineRelated: It preceded vaccination and demonstrated that induced exposure could prevent severe smallpox.SmallpoxRelated: This risky predecessor to vaccination used smallpox itself to prevent later disease.Smallpox vaccineCompared with: It used variola itself and carried greater risk than vaccination with a related virus.Edward JennerCompared with: Jenner’s approach sought smallpox protection without deliberately exposing people to smallpox itself.Lady Mary Wortley MontaguRelated: Montagu observed this practice in Constantinople and promoted it in Britain.