Linked from

The 14 pages that link to X-inactivation, each with the reason it gives.

• Turner syndromeRelated: Variable escape from X-inactivation informs hypotheses about dosage-sensitive genes in Turner syndrome.

• X chromosomeRelated: This dosage-compensation process balances much X-linked gene expression between sexes.

• X-linked recessive inheritanceRelated: Uneven silencing can cause symptoms in some females who carry an X-linked variant.

• HaploinsufficiencyRelated: Mosaic expression after X-inactivation can alter the effects of variants in X-linked genes.

• Klinefelter syndromeRelated: Incomplete silencing of some genes helps explain effects of the additional X chromosome.

• Sex-linked inheritanceRelated: Random X-inactivation can create cellular mosaics in heterozygous individuals.

• Fragile X syndromeRelated: Differences in which X chromosome remains active help explain variable effects in females.

• Rett syndromeRelated: Variable X-inactivation can help explain differences in severity among people with MECP2 variants.

• X-linked dominant inheritanceRelated: Uneven silencing can shape symptom severity in heterozygous individuals.

• Tetrasomy XRelated: X-inactivation moderates gene dosage, though some genes escape silencing.

• Aicardi syndromeRelated: Uneven X-inactivation has been investigated as a possible influence on disease severity.