KnowraAmyotrophic lateral sclerosisLinked fromLinked fromThe 21 pages that link to Amyotrophic lateral sclerosis, each with the reason it gives.All 21Broader topic 6Related 10Narrower topic 1Compared with 4NeurodegenerationBroader topic: It demonstrates neurodegeneration in both upper and lower motor neuron systems.Muscle weaknessBroader topic: It demonstrates how motor-neuron loss produces progressive weakness.Protein misfoldingBroader topic: Protein aggregation and misfolding are implicated in several genetic and sporadic forms.Jean-Martin CharcotBroader topic: Charcot and Alexis Joffroy described its clinical and pathological features; it was once called Charcot disease.Lower motor neuronBroader topic: Its lower motor neuron damage causes weakness, muscle wasting, and fasciculations.Neurodegenerative diseaseBroader topic: It illustrates degeneration affecting motor pathways in the brain and spinal cord.