Linked from

The 35 pages that link to Aspirin, each with the reason it gives.

• Nonsteroidal anti-inflammatory drugBroader topic: Its antiplatelet effect gives it uses beyond ordinary pain relief.

• EsterificationRelated: Its synthesis includes acetylation of salicylic acid, forming an ester group.

• EsterRelated: Its ester linkage is cleaved during metabolism and contributes to its chemical reactivity.

• Myocardial infarctionRelated: Early aspirin reduces further clot growth in suspected acute infarction.

• PlateletCompared with: It suppresses platelet activation to lower the risk of arterial clot formation.

• CyclooxygenaseRelated: Its long-known physiological effects motivated the search for the biochemical target.

• ProstaglandinBroader topic: It is a widely used example of pharmacological blockade of prostaglandin synthesis.

• AcetaminophenCompared with: Aspirin affects platelets and inflammation more than acetaminophen, with distinct bleeding and pediatric risks.

• Arachidonic acidBroader topic: Its inhibition of cyclooxygenase reduces arachidonic-acid-derived prostaglandins and thromboxanes.

• Salicylic acidRelated: Aspirin is made by acetylating salicylic acid's phenolic hydroxyl group.

• WarfarinCompared with: It acts on platelets rather than vitamin K-dependent clotting factors.

• EicosanoidRelated: Its effects on prostaglandins and thromboxane explain its uses in pain relief and prevention of some clots.

• IbuprofenCompared with: Unlike ibuprofen’s reversible inhibition, aspirin permanently disables platelet COX for the life of each platelet.

• ParacetamolCompared with: Aspirin affects platelets and inflammation in ways paracetamol generally does not.

• Natural productRelated: Its history connects plant-derived compounds with the rise of modern pharmaceutical chemistry.

• Brønsted–Lowry acidBroader topic: Its carboxyl group can donate a proton, influencing its solubility and absorption.

• Ester hydrolysisRelated: Hydrolysis converts aspirin into salicylic acid and acetic acid, including during metabolism.

• Lynch syndromeRelated: Clinical evidence supports discussing aspirin chemoprevention with some people who have Lynch syndrome.

• Phenyl groupBroader topic: Its aromatic ring is part of a substituted phenyl framework.

• AntipyreticBroader topic: It reduces fever but is generally avoided in children with viral illnesses.

• Chemical compoundBroader topic: Its defined molecular structure supports both pharmaceutical action and chemical synthesis.

• ClopidogrelRelated: It is often paired with clopidogrel because the drugs inhibit different platelet pathways.

• Enteric coatingRelated: Enteric-coated aspirin is intended to reduce direct exposure of the stomach lining to the drug.

• BayerBroader topic: Bayer commercialized aspirin in 1899, making it one of its best-known early medicines.

• Carbonyl compoundBroader topic: Its two carbonyl-containing groups illustrate carbonyl chemistry in a widely used medicine.

• SalixRelated: The drug's history is linked to salicin, a compound found in willow bark.

• Acetic anhydrideBroader topic: Its manufacture commonly acetylates salicylic acid with acetic anhydride.

• NaproxenCompared with: Unlike naproxen, aspirin’s platelet effect persists for the lifespan of affected platelets.

• SalicinRelated: Salicin’s historical association with willow helped motivate the search for useful salicylate medicines.

• ErythromelalgiaRelated: It can markedly relieve erythromelalgia associated with essential thrombocythemia or other platelet disorders.

• MetamizoleCompared with: Aspirin is an alternative analgesic and antipyretic whose platelet effects distinguish it from metamizole.

• Salix albaRelated: Willow-derived salicin helped inspire the development of aspirin, though aspirin is a distinct compound.

• PhenacetinCompared with: Aspirin became a major alternative analgesic as concerns grew over phenacetin.

• IndometacinCompared with: Its lasting platelet effect contrasts with indometacin’s reversible enzyme inhibition.

• PiroxicamCompared with: Its lasting platelet effect and distinct uses separate it from piroxicam’s reversible enzyme inhibition.