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The 102 pages that link to Blood–brain barrier, each with the reason it gives.

• Lead poisoningRelated: Lead can cross this protective interface, particularly in children.

• Multiple sclerosisRelated: Changes in barrier function can enable immune cells to enter nervous tissue.

• Cerebrospinal fluidCompared with: Unlike cerebrospinal fluid circulation, this barrier controls molecular passage into brain tissue.

• RabiesRelated: Rabies reaches the brain mainly through nerves rather than by crossing this barrier from blood.

• Traumatic Brain InjuryRelated: Trauma can disrupt this barrier, contributing to inflammation and tissue injury.

• Central nervous systemRelated: It protects central nervous system tissue but also limits delivery of many medicines.

• Drug deliveryRelated: Its selectivity makes drug access to the central nervous system a delivery challenge.

• CapillaryBroader topic: Brain capillaries have unusually tight junctions that restrict exchange and protect neural tissue.

• NeuroinflammationRelated: Inflammation can change its permeability and influence immune-cell entry.

• EndotheliumBroader topic: It is a highly specialized endothelial barrier with distinctive transport and sealing properties.

• PrionRelated: It shapes how prions reach the central nervous system after peripheral exposure.

• Histamine H1 receptorRelated: Whether an H1-blocking drug crosses this barrier strongly affects sedation.

• LeadRelated: Lead exposure can impair this protective interface, especially during brain development.

• Status epilepticusRelated: Prolonged seizures can disrupt this barrier and alter brain exposure to circulating substances.

• AntihistamineRelated: How readily a drug crosses it helps explain why some antihistamines cause drowsiness.

• Mercury poisoningRelated: Methylmercury can cross it, helping explain mercury’s neurological effects.

• Minamata diseaseRelated: Methylmercury can cross this barrier and injure the central nervous system.

• Enzyme replacement therapyRelated: Most infused replacement enzymes cannot cross it, limiting treatment of neurological disease.

• MeningesCompared with: It controls exchange at brain capillaries, unlike the meninges’ enclosing and protective layers.

• Endothelial cellBroader topic: Brain endothelial cells form unusually restrictive junctions that limit exchange with neural tissue.

• MeningitisRelated: Pathogens that cross this protective interface can reach the meninges and cerebrospinal fluid.

• Hepatic encephalopathyRelated: Its altered permeability during illness may affect how circulating toxins influence the brain.

• IvermectinRelated: In mammals, this barrier and drug-efflux transporters help restrict ivermectin from sensitive central nervous system targets.

• NeurotoxinRelated: Its permeability helps determine which circulating toxins can reach the central nervous system.

• AstrocyteRelated: Astrocyte endfeet help maintain the barrier's properties and coordinate it with neural tissue.

• Cerebral edemaRelated: Damage to this barrier lets fluid and proteins leak into brain tissue, producing vasogenic edema.

• NeurotoxicityRelated: Its disruption can let otherwise restricted toxic substances reach brain tissue.

• PralidoximeRelated: Limited central nervous system penetration may leave some effects insufficiently treated.

• EncephalitisRelated: Infection and inflammation can disrupt this barrier and alter immune access to the brain.

• P-glycoproteinRelated: P-glycoprotein at this barrier exports many compounds and restricts their brain entry.

• ScopolamineRelated: Scopolamine enters the brain, contributing to sedation and possible confusion.

• HeroinRelated: Heroin crosses it readily, helping explain its rapid effects.

• LevodopaRelated: Levodopa crosses this barrier, while dopamine itself crosses poorly.

• MethylmercuryRelated: Methylmercury can cross this barrier, enabling direct exposure of nervous tissue.

• MetoclopramideRelated: Metoclopramide enters the central nervous system, helping cause neurological adverse effects.

• PericyteRelated: Pericytes help maintain barrier properties in brain vessels and influence their permeability.

• PropranololRelated: Propranolol crosses this barrier, a property relevant to its central nervous system effects.

• Glomerular filtration barrierRelated: It is another selective blood-tissue interface, but uses a distinct cellular architecture and serves a different organ.

• MicrocirculationBroader topic: It is a highly selective form of microvascular exchange.

• Psychiatric medicationRelated: A psychiatric drug must reach relevant brain sites to produce central effects.

• PsychopharmacologyRelated: A psychiatric drug must reach relevant brain tissue to act there.

• BrainRelated: It protects the brain while controlling its access to nutrients and circulating chemicals.

• Brain tumorRelated: This barrier limits delivery of many drugs to tumors within brain tissue.

• DiphenhydramineRelated: Diphenhydramine crosses this barrier, contributing to central sedation and impaired alertness.

• Intracranial hemorrhageRelated: A hemorrhage breaches vessels that normally keep blood separate from brain tissue.

• LeptinRelated: How leptin reaches relevant brain circuits may constrain signaling in obesity.

• NeurocysticercosisRelated: Larval invasion and inflammation alter this barrier, affecting symptoms and drug access.

• Anticholinergic syndromeRelated: Whether a drug enters the brain helps determine the severity of confusion, agitation, or delirium.

• Bacterial meningitisRelated: Some bacteria cross this interface from the bloodstream to enter the central nervous system.

• CetirizineRelated: Limited penetration across this barrier helps explain cetirizine’s lower, but not absent, sedation.