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The 102 pages that link to Blood–brain barrier, each with the reason it gives.

• Chemoreceptor trigger zoneRelated: The area postrema’s weak barrier protection lets circulating chemicals reach its sensory cells.

• GlioblastomaRelated: It limits delivery of some anticancer drugs to glioblastoma cells.

• Glutamic acidRelated: Its restriction of circulating glutamate helps keep brain neurotransmitter pools locally controlled.

• MannitolRelated: Intravenous mannitol changes osmotic gradients across this barrier to reduce brain swelling.

• Second-generation antihistamineRelated: Limited passage across this barrier is the design feature that reduces central effects.

• Wernicke encephalopathyRelated: Thiamine transport across this barrier helps explain how deficiency affects the brain.

• Antisense oligonucleotideRelated: Its limited permeability complicates delivery to brain and spinal-cord targets.

• Chronic traumatic encephalopathyRelated: Repeated impacts may disrupt this barrier, though its role in CTE development is not settled.

• Trypanosoma bruceiRelated: In late human disease, parasites enter the central nervous system and disrupt sleep and neurological function.

• Adenosine receptor antagonistRelated: Central effects of antagonists depend partly on whether they cross this barrier.

• CysticercosisRelated: Its permeability and inflammation influence how drugs reach brain cysts.

• Listeria monocytogenesRelated: Invasive listeriosis can involve the central nervous system after the bacterium reaches this barrier.

• Nervous tissueRelated: This barrier protects central nervous tissue while controlling access to its chemical environment.

• African trypanosomiasisRelated: Parasite entry into the central nervous system marks the second stage of human sleeping sickness.

• Harvey CushingRelated: Its protective anatomy makes intracranial surgery and tumor treatment distinctive.

• HydroxyzineRelated: Hydroxyzine enters the brain, helping explain its sedating effects.

• NeurosyphilisRelated: Its relationship to treponemal invasion helps explain how infection reaches the nervous system.

• Progressive multifocal leukoencephalopathyRelated: Immune-cell access to the central nervous system shapes viral control and disease risk.

• PromethazineRelated: Promethazine crosses this barrier, helping explain its central sedation and effects on nausea.

• West Nile feverRelated: When West Nile virus reaches the nervous system, disease can become neuroinvasive.

• Cell junctionRelated: Endothelial tight junctions restrict movement from blood into the brain.

• Glymphatic systemRelated: It separates vascular blood from tissue fluid, making the proposed perivascular route distinct from ordinary blood exchange.

• HyperammonemiaRelated: Ammonia crosses into the brain, where its handling differs from its handling in blood.

• LipophilicityRelated: Lipophilicity can aid passive entry, but excessive lipophilicity may hinder useful brain exposure.

• LoratadineRelated: Loratadine enters the brain less readily than older antihistamines, helping limit sedation.

• Maple syrup urine diseaseRelated: Excess branched-chain amino acids can disrupt amino-acid transport into the brain.

• Neuromyelitis optica spectrum disorderRelated: Its disruption enables circulating immune factors to reach vulnerable central nervous system tissue.

• Blood-retinal barrierRelated: It shares endothelial tight-junction principles with the inner retinal barrier.

• EndorphinsRelated: This barrier helps explain why circulating peptides and brain-produced endorphins have different access to neural tissue.

• LoperamideRelated: Together with P-glycoprotein, it helps explain loperamide’s limited central opioid effects at recommended doses.

• TemozolomideRelated: Temozolomide crosses this barrier sufficiently to treat tumors within the central nervous system.

• Blood-nerve barrierCompared with: It shares a vascular barrier design but protects central rather than peripheral nervous tissue.

• Brain injuryRelated: Injury can disrupt this barrier, changing fluid balance and immune access.

• DesloratadineRelated: Limited brain entry helps explain why desloratadine is less sedating than older antihistamines.

• DomperidoneRelated: Domperidone crosses it poorly, limiting central effects and some neurological adverse effects.

• Metal toxicityRelated: Metal entry across this barrier helps determine whether exposure causes neurological injury.

• PseudoephedrineRelated: Pseudoephedrine’s limited central penetration helps distinguish its effects from stronger stimulants.

• GliaRelated: Astrocytes help maintain barrier properties through interactions with brain blood vessels.

• Human brainRelated: It protects the brain while shaping its access to nutrients and medicines.

• NeuropsychiatryRelated: Its disruption can expose the brain to immune or metabolic influences that alter behavior.

• Ramón Villeda MoralesRelated: It shapes which circulating signals can influence the brain.

• Anti-NMDA receptor encephalitisRelated: Access to the central nervous system helps shape how circulating immune responses affect the brain.

• Blood–air barrierCompared with: Unlike the lung interface, it restricts many substances rather than enabling rapid gas exchange.

• Blood–spinal cord barrierCompared with: It shares core barrier features with the spinal cord interface but serves brain tissue.

• Brain (anatomy)Related: It protects the brain’s chemical environment while restricting access for many molecules.

• DimethylmercuryRelated: Methylmercury formed from dimethylmercury can cross this protective interface.

• Fluids and SecretionsRelated: It limits which circulating substances can enter brain tissue and cerebrospinal fluid.

• Hunter syndromeRelated: Its limited permeability helps explain why enzyme replacement does not adequately treat neurological disease.

• Japanese encephalitisRelated: Neurological disease develops when infection reaches the central nervous system despite this protective barrier.

• Primary amoebic meningoencephalitisRelated: PAM reaches the brain from the nasal route rather than typically crossing this blood-based interface.