Linked from

The 15 pages that link to Codeine, each with the reason it gives.

• Drug metabolismBroader topic: Its variable activation makes enzyme genetics clinically consequential.

• MorphineCompared with: Codeine is less potent and partly relies on conversion to morphine for analgesia.

• HeroinCompared with: It is a less potent opioid alkaloid that can be metabolized into morphine.

• CYP2D6Related: CYP2D6 activity affects how much morphine codeine can produce.

• Active metaboliteRelated: Its conversion to morphine illustrates how an active metabolite can mediate a parent drug’s effects.

• OpiumBroader topic: It is another naturally occurring opium alkaloid, with weaker analgesic effects than morphine.

• DextromethorphanCompared with: Codeine suppresses cough through opioid receptors and carries opioid-related risks.

• AntitussiveBroader topic: Its action on opioid receptors can reduce the brain’s cough response.

• Papaver somniferumBroader topic: It is another naturally occurring alkaloid in the plant’s latex.

• TramadolCompared with: Like tramadol, its effects vary with CYP2D6 activity, but it lacks tramadol’s serotonin reuptake inhibition.

• PapaverineCompared with: Codeine is an opioid, whereas papaverine primarily relaxes smooth muscle.

• HydrocodoneCompared with: Both drugs rely partly on CYP2D6 metabolism, but codeine is less potent.

• PethidineCompared with: Codeine is generally used for less severe pain and relies on metabolism unlike pethidine’s active neurotoxic metabolite.

• ThebaineRelated: Both compounds occur in opium, but thebaine is more chemically reactive and convulsant.

• DesomorphineCompared with: Codeine is a less potent opioid with different clinical uses and effects.