Linked from

The 14 pages that link to Interleukin 6, each with the reason it gives.

• Multiple myelomaRelated: Marrow signaling through interleukin 6 can support myeloma-cell survival and growth.

• C-reactive proteinRelated: It is a major signal prompting liver cells to increase CRP production during inflammation.

• Tumor necrosis factorCompared with: It can cooperate with TNF in inflammation, while having distinct signaling pathways and clinical targets.

• Cytokine stormBroader topic: Elevated levels can accompany severe inflammatory responses and guide treatment in some settings.

• JAK-STAT signaling pathwayBroader topic: Its receptor activates JAK-STAT signaling and contributes to inflammatory disease.

• Cytokine release syndromeBroader topic: Elevated IL-6 is associated with fever, vascular changes, and severe CRS.

• TocilizumabRelated: Blocking its receptor interrupts the inflammatory signals driven by this cytokine.

• Polymyalgia rheumaticaRelated: Its inflammatory signaling may contribute to disease activity and provides a target for steroid-sparing therapy.

• Giant cell arteritisRelated: Its activity contributes to systemic inflammation and elevated inflammatory markers.

• Neuromyelitis optica spectrum disorderRelated: Elevated signaling can support pathogenic antibody production and inflammatory attacks in the disorder.

• Castleman diseaseRelated: Excess IL-6 signaling contributes to inflammation and many systemic symptoms.

• Jarisch–Herxheimer reactionRelated: Elevated levels are associated with the reaction’s fever and inflammatory symptoms.

• Adult-onset Still's diseaseRelated: Its inflammatory signaling contributes to fever and elevated inflammatory markers.

• Antibody-producing cellsRelated: This cytokine is among the signals associated with plasma-cell differentiation and persistence.