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The 19 pages that link to Nicotinic acetylcholine receptor, each with the reason it gives.

• AcetylcholineBroader topic: At neuromuscular junctions, this receptor converts acetylcholine release into a muscle-cell electrical signal.

• Neuromuscular junctionBroader topic: Its opening produces the end-plate current that initiates muscle excitation.

• Muscarinic acetylcholine receptorCompared with: Unlike muscarinic receptors, it directly conducts ions rather than signaling through G proteins.

• GABA receptorCompared with: Unlike GABA-A channels, it generally depolarizes cells through cation flow.

• Parasympathetic nervous systemBroader topic: Parasympathetic preganglionic fibers activate nicotinic receptors on postganglionic neurons.

• NicotineBroader topic: Nicotine binds these receptors, triggering ion flow and changes in neuronal activity.

• Adrenal medullaRelated: Chromaffin-cell receptors convert nerve-released acetylcholine into electrical excitation.

• PralidoximeRelated: Excess signaling at these receptors contributes to fasciculations, weakness, and paralysis.

• Cholinergic crisisBroader topic: Excess activation first causes muscle twitching and can progress to weakness or paralysis.

• SarinBroader topic: Excess acetylcholine overstimulates these receptors, causing fasciculations and paralysis.

• AnticholinergicBroader topic: Some anticholinergic agents act at these receptors rather than muscarinic ones.

• Chromaffin cellsRelated: These receptors convert splanchnic nerve signals into chromaffin-cell depolarization.

• Nicotine dependenceBroader topic: Nicotine binds these receptors, initiating signals that reinforce repeated use.

• Tropane alkaloidRelated: Some tropane compounds, including cocaine, also interact with nicotinic receptors.

• NeostigmineRelated: More acetylcholine helps activate these receptors at the neuromuscular junction.

• DonepezilBroader topic: Extra acetylcholine can also affect these receptors in brain circuits involved in cognition.

• Henry Hallett DaleBroader topic: It is the receptor mechanism underlying acetylcholine’s rapid action at skeletal muscle.

• Conium maculatumBroader topic: Conium alkaloids disrupt signaling at these receptors, impairing muscle control.

• MuscarineCompared with: Unlike acetylcholine, muscarine selectively activates muscarinic rather than nicotinic receptors.