KnowraNicotinic acetylcholine receptorLinked fromLinked fromThe 19 pages that link to Nicotinic acetylcholine receptor, each with the reason it gives.All 19Broader topic 11Related 5Compared with 3AcetylcholineBroader topic: At neuromuscular junctions, this receptor converts acetylcholine release into a muscle-cell electrical signal.Neuromuscular junctionBroader topic: Its opening produces the end-plate current that initiates muscle excitation.Parasympathetic nervous systemBroader topic: Parasympathetic preganglionic fibers activate nicotinic receptors on postganglionic neurons.NicotineBroader topic: Nicotine binds these receptors, triggering ion flow and changes in neuronal activity.Cholinergic crisisBroader topic: Excess activation first causes muscle twitching and can progress to weakness or paralysis.SarinBroader topic: Excess acetylcholine overstimulates these receptors, causing fasciculations and paralysis.AnticholinergicBroader topic: Some anticholinergic agents act at these receptors rather than muscarinic ones.Nicotine dependenceBroader topic: Nicotine binds these receptors, initiating signals that reinforce repeated use.DonepezilBroader topic: Extra acetylcholine can also affect these receptors in brain circuits involved in cognition.Henry Hallett DaleBroader topic: It is the receptor mechanism underlying acetylcholine’s rapid action at skeletal muscle.Conium maculatumBroader topic: Conium alkaloids disrupt signaling at these receptors, impairing muscle control.