KnowraPaget's disease of boneLinked fromLinked fromThe 7 pages that link to Paget's disease of bone, each with the reason it gives.All 7Related 3Compared with 4OsteoclastRelated: Abnormally increased osteoclast activity initiates the excessive remodeling seen in the disease.Alkaline phosphataseRelated: Active disease can raise circulating bone-derived alkaline phosphatase.OsteosarcomaRelated: In older adults, this disorder is associated with a rare form of secondary osteosarcoma.