Linked from

The 25 pages that link to Prion, each with the reason it gives.

• ProteinBroader topic: Prions demonstrate that a protein’s shape can transmit biological information.

• Protein foldingBroader topic: Prions show how a protein conformation can template misfolding in other molecules.

• Protein denaturationRelated: Prion diseases show how altered protein structure can propagate and cause biological harm.

• PathogenCompared with: Prions cause transmissible disease but are not biological organisms like the main pathogen groups.

• Cell theoryRelated: Prions reproduce biological patterns without cells, distinguishing propagation from cellular reproduction.

• VirusCompared with: Prions are infectious agents but lack the genomes found in viruses.

• GelatinRelated: Concern about animal-derived materials has led regulators to control sourcing and processing for transmissible agents.

• Central dogma of molecular biologyCompared with: Prions transmit structural states, not protein sequence information back to nucleic acids.

• AmyloidRelated: Prions demonstrate how protein conformations can propagate through templated aggregation.

• Epigenetic inheritanceRelated: Prion conformations show how cellular states can be inherited through protein copying rather than DNA.

• Beta sheetRelated: Prion propagation can involve conversion into beta-sheet-rich assemblies.

• Creutzfeldt–Jakob diseaseNarrower topic: Misfolded prion protein drives the brain damage in this disease.

• KuruNarrower topic: Kuru is caused by infectious prions that accumulate in the nervous system.

• Bovine spongiform encephalopathyNarrower topic: Misfolded prion protein is the infectious agent that causes the disease.

• Life (biology)Compared with: Prions transmit structural information without cells, genes, or metabolism.

• OrganismCompared with: Prions can spread and cause disease without cells, genes, or metabolism.

• Obligate intracellular parasiteCompared with: Prions depend on host molecules but are not organisms that reproduce inside cells.

• Variant Creutzfeldt–Jakob diseaseNarrower topic: Variant CJD is caused by prions that convert the brain’s normal prion protein into an abnormal form.

• Stanley B. PrusinerBroader topic: Prusiner named and characterized the protein-based infectious agent at the center of his work.

• Transmissible spongiform encephalopathyNarrower topic: Misfolded prion protein drives the tissue damage and infectivity characteristic of these diseases.

• Christian B. AnfinsenCompared with: Prions show that a protein’s structure can depend on an existing template, not sequence alone.

• Daniel Carleton GajdusekCompared with: Prions replaced the viral-agent explanation Gajdusek initially favored.

• Gerstmann–Sträussler–Scheinker syndromeNarrower topic: Misfolded prion protein accumulates in the brain and drives neuronal injury.

• Macromolecule (biochemistry)Related: Prions show how a macromolecule’s structure can carry biological activity without nucleic acid.

• Non-cellular lifeBroader topic: Prions transmit biological information without cells or nucleic acids.