KnowraPyruvate dehydrogenase complexLinked fromLinked fromThe 8 pages that link to Pyruvate dehydrogenase complex, each with the reason it gives.All 8Related 5Compared with 3Acetyl-CoARelated: It makes acetyl-CoA from glucose-derived pyruvate.DecarboxylationRelated: Its E1 subunit catalyzes a cofactor-dependent decarboxylation of pyruvate.ThiamineRelated: Its first catalytic step requires thiamine pyrophosphate to process carbohydrate-derived pyruvate.Leigh syndromeRelated: Defects can impair energy metabolism and produce a Leigh syndrome presentation.Pyruvic acidRelated: This reaction commits pyruvate to aerobic oxidation and links glycolysis to the citric acid cycle.