KnowraSecond-generation antihistamineLinked fromLinked fromThe 8 pages that link to Second-generation antihistamine, each with the reason it gives.All 8Broader topic 2Related 1Narrower topic 1Compared with 4Histamine H1 receptorCompared with: These drugs target peripheral H1 effects with less influence on wakefulness.AntihistamineBroader topic: Their reduced brain penetration helps distinguish them from older antihistamines, though drowsiness can still occur.UrticariaRelated: These medicines are the usual first-line treatment for urticaria symptoms.HydroxyzineCompared with: This newer group is typically less sedating than hydroxyzine.PromethazineCompared with: This drug class contrasts with promethazine's brain-penetrating, often drowsy-making profile.DesloratadineNarrower topic: Desloratadine belongs to this class of allergy medicines.HivesBroader topic: These medicines are commonly used as first-line treatment for uncomplicated hives.CyclizineCompared with: These drugs usually treat allergies rather than motion sickness because they have less central action.